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- W2370152076 abstract "Uterine horn injection method was conducted to explore the impact of nitric oxide(NO) on the embryonic implantation of mouse,meanwhile,the tissue section and light microscope were taken to observe the impacts of NO on the uterus of mouse,the morphological changes of endometrium and the uterine decidua.The results showed that in comparison with control,the number of implanted embryo declined in L-NAME(0.2 mg/mice) group,but no impact when added NO donor sodium nitroprusside(SNP) to L-NAME.During the process of embryonic implantation,the pregnant side of uterine had the obviously developed endometrium,the increased epithelial cells,the developed glandular organ,the loose mesenchymal and the augmented interstitial cells,which had significantly decidua transformation.The inhibited side of uterine had comparatively lower endometrial epithelial cells and the lower number of glandular organ,the pronouncedly degenerative endometrium in the later period of embryonic implantation and the compact matrix.Therefore,NO,as a endogenous smooth muscle relaxant and vasodilator,has a significant regulatory effect on the expression of MMP-9 mRNA in endometrium.The inhibition of nitric oxide synthase significantly will drop the gene expression of MMP-9 in endometrium in the process of implantation,and it will affect the endometrial development and embryonic implantation in further." @default.
- W2370152076 created "2016-06-24" @default.
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- W2370152076 date "2010-01-01" @default.
- W2370152076 modified "2023-09-24" @default.
- W2370152076 title "Impact of Nitric Oxide on the Embryonic Implantation of Mouse" @default.
- W2370152076 hasPublicationYear "2010" @default.
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