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- W2370174032 abstract "Objective: To investigate the expression of cyclooxygenase-2(COX-2) and vascular endothelial growth factor(VEGF) in oral mucosa squamous cell carcinoma tissue,and to explore the relationship and significance of them.Methods: The expression of COX-2 and VEGF in 54 cases of oral mucosa squamous cell carcinoma tissue were detected by immunohistochemistry SP staining and its correlations to clinicopathologic features were analyzed.Results: The positive expression rate of COX-2 and VEGF was 55.6%,62.5 % respectively.The positive expression of COX-2 and VEGF was correlated with pathological grade,TNM stage and tumor recurrence(P0.05).There were positive correlations between the expression of COX-2 and VEGF(r=0.549,P0.05).Conclusion: The expression of COX-2 and VEGF are both higher,and they are closely correlated to biological action of oral mucosa carcinoma that play an important role in its development.It may be used as new targets for early diagnosis and treatment of patients with oral mucosa squamous cell carcinoma." @default.
- W2370174032 created "2016-06-24" @default.
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- W2370174032 date "2012-01-01" @default.
- W2370174032 modified "2023-09-22" @default.
- W2370174032 title "The Expression and Significance of Cox-2 and VEGF in Oral Mucosa Squamous Cell Carcinoma" @default.
- W2370174032 hasPublicationYear "2012" @default.
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