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- W2370279915 abstract "Thirty cases of severe dysfunctional uterine bleeding in climacteric women, who had been treatedwith other drugs without effect and were going to have operative procedures, were treated with hydroxypro-gesterone caproate. The serum estradiol(E2)level in patients before treatment was significantly higher than that in control group(P0.01),suggesting that increase in estrogen might be the major factor in stimulat-ing endometrial hyperplasia. The serum levels of E2,FSH and LH in the patients decreased significantly after treatment(P0. 01 ),suggesting that hydroxyprogesterone caproate could not only act directly against thestimulating effect of estrogen on the endometrium,but also inhibit the functions of hypothalamus and pitu-itary through central nervous system,thus lowered the secretions of FSH and LH and the serum E2 level,andfinally converted the various types of endometrial hyperplasia to normal proliferative phase or secretoryphase." @default.
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- W2370279915 date "1994-01-01" @default.
- W2370279915 modified "2023-09-23" @default.
- W2370279915 title "Hydroxyprogesterone caproate for 30 cases of severe dysfunctional u-terine hemorrhage in climacteric women" @default.
- W2370279915 hasPublicationYear "1994" @default.
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