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- W2370284358 abstract "[Objective]To explore the efficacy of Ursodeoxycholic acid in combination with principles of emolliating the liver,invigorating the spleen,promoting blood flow and deoppilation the bile on treating primary biliary cirrhosis.[Methods]In a randomized trial,33 selected caseswere divided into contrast group(n=16) and treatment group(n=17),corresponding to give the therapeutics of ursodeoxycholic acid and integrated Chinese medicine with ursodeoxycholic acid.The clinical efficacy,the relation of clinical stages and biochemical indicator and the amelioration of biochemical indicator were observed.[Results]①The clinical symptoms and physical signs in both groups had distinct amelioration after treatment.The improvement of clinical symptoms in treatment group was more significant than that in the control group(P0.05);②The TBil increased gradually,and the ALT decreased significantly,in adversely the AST present ascensus in advanced stage cases.The ALT and TBil present enzyme and cholerythrogen segregation phenomenon in comparison with the result of the earlier period,intermediate stage and advanced stage,The ALP and GGT obviously increased in earlier period and significantly descend in advanced stage,but the Alb took on descensus tendency;③The biochemical indicators of two group patients both had amelioration after treatment,and the treatment group was more significantly in amelioration with the patients serum TBil and GGT(P0.01).[Conclusion]Integrated Chinese medicine with Ursodeoxycholic acid obviously improves the symptoms and physical signs of the patients with primary biliary cirrhosis,and raises clinical cure rate and effective power,accordingly improve the quality of life of the patients,it can reduce the probability of liver transplantation." @default.
- W2370284358 created "2016-06-24" @default.
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- W2370284358 date "2009-01-01" @default.
- W2370284358 modified "2023-09-27" @default.
- W2370284358 title "Efficacy of ursodeoxycholic acid in combination with principles of emolliating the liver,invigorating the spleen,promoting blood flow and deoppilation the bile for treating primary biliary cirrhosis" @default.
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