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- W2370291373 abstract "Objective To investigate the histological maturity of“regenerated”mucosa in duode-nal ulcer (DU) after triple therapy with omeprazole,clarithromycin and tinidazole.Methods Sixty-fourpatients with Helicobacter pylori (HP) positive active DU were randomly divided into 2 groups:group A(n=36) with omeprazole 20mg,clarithromycin 500mg and tinidazole 500mg (LCT) twice daily for oneweek;group B (n =28) with ranitidine 150mg twicc daily,amoxicillin 500mg thrice daily and metron-idazole 400mg thrice daily (RAM) for 4 weeks.Results Three cases in group A and 2 in group B werelost during follow-up.30 of 33 patients in group A were healed(90.91%) at 4 ~6 weeks after the end oftreatment,18 of 26 patients in group B were healed (69.23%),P0.05;The eradication rates of HP ingroup A and group B were 93.94%,65.38%,P0.05;For histological maturity of“regenerated”muco-sa,22 of 30 patients in group A were“good”(73.33%),but only 6 of 18 patients in group B (33.33%),P0.01.Conclusion After one-week triple therapy with omeprazole,clarithromycin and tini-dazole,the eradication rates of HP were high.The histological maturity of“regenerated”mucosa in patientswith LCTtreatment is preferred to that in patients with RAM treatment." @default.
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- W2370291373 date "2005-01-01" @default.
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- W2370291373 title "A study on histological maturity of healed duodenal ulcer after triple therapy with omeprazole,clarithromycin and tinidazole" @default.
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