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- W2370303359 abstract "Objective:To investigate the effect of Liuwei Dihuang decoction metabolized by photosynthetic bacteria(LW-PSB) on the expression of Bcl-2 and Bax mRNA in hippocampus neurons of aging model mice.Method:Mice were randomly divided into 4 groups: model group,positive control group(VE 0.27 g · kg-1),LW-PSB-treated group(0.50 g · kg-1) and normal group.Each group was administrated continuously for 30 days.After 30 min of administration,the hippocampus of each group was separated and RT-PCR was adopted to detect the expression of Bcl-2 and Bax mRNA in hippocampus neurons.Result:Compared with the model group and positive control group,the Bcl-2 2-△△Ct and Bcl-2/Bax were increased and Bax 2-△△Ctwas decreased in LW-PSB-treated group.Conclusion:LW-PSB might up-regulate expression of Bcl-2 mRNA and down-regulate expression of Bax mRNA to anti-aging." @default.
- W2370303359 created "2016-06-24" @default.
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- W2370303359 date "2012-01-01" @default.
- W2370303359 modified "2023-09-23" @default.
- W2370303359 title "Effect of Liuwei Dihuang Decoction Metabolized by Photosynthetic Bacteria on the Expression of Bcl-2 and Bax mRNA in Hippocampus Neurons of Aging Model Mice" @default.
- W2370303359 hasPublicationYear "2012" @default.
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