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- W2370307533 abstract "A 56-years-old man with advanced primary hepatocarcinoma developed hyperpyrexia after receiving 8 days of recommended dose of sorafenib tosylate 0.4 g q12h treatment,his topmost body temperature was 39.3 ℃,and from the 11th of administration skin rash emerged,so he was readmitted.After admission,sorafenib tosylate was suspended and the patient was administered with anti-allergic treatment for 5 days.After these treatments his symptoms disappeared.Five days later low dose of sorafenib tosylate 0.2 g q12h treatment was administered for 5 days,hyperpyrexia and skin rash did not occur.Then recommended dose of sorafenib tosylate 0.4 g q12h was administered for another 1 day,hyperpyrexia and skin rash reoccurred.Sorafenib was suspended again for 3 days and his symptoms improved.Then low dose of sorafenib tosylate(0.2 g q12h) was administered again,his vital sign and condition were stable without hyperpyrexia and new skin rash.This paper will be helpful to clinical physicians in diagnosing and managing drug fever." @default.
- W2370307533 created "2016-06-24" @default.
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- W2370307533 date "2013-01-01" @default.
- W2370307533 modified "2023-09-28" @default.
- W2370307533 title "Hyperpyrexia accompanying rash associated with sorafenib tosylate in a patient with advanced hepatocellular carcinoma" @default.
- W2370307533 hasPublicationYear "2013" @default.
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