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- W2370331831 abstract "Objective To investigate the influence of the different dialysis membrane on the interleukin - 8 expression in uremic patients. Methods The plasma concentration of IL- 8 and the IL- 8 production by the cultivated PBMC were measured with enzyme - linked immunoabsorbent assay (FLISA). The gene expression of IL-8 was measured with reverse transcription - polymerase chain reaction(RT - PCR) . Results The IL - 8 plasma and mRNA level of the patients using the regenerated cellulose membrane (cuprophan CU, cuprammonium rayon CR) is higher than that of those using polysulfone (PS) membrane. The IL- 8 plasma level and mRNA expression increases after hemodialysis. The production of IL- 8 from PBMC of the patients using CU membrane was more than that of those using PS membrane. In PS group the IL - 8 production of PBMC increased after dialysis. But there was no obvious difference of IL - 8 production from PBMC between pre - dialysis and post - dialysis in CU group. Conclusion The change of IL - 8 mRNA expression and plasma level through the hemodialysis in the regenerated cellulose membrane (especially CU) groups is more significant than that in PS group. The measurement of IL - 8 expression is useful to evaluate the biocompatibility of dialysis membranes." @default.
- W2370331831 created "2016-06-24" @default.
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- W2370331831 date "2002-01-01" @default.
- W2370331831 modified "2023-09-26" @default.
- W2370331831 title "Influence of the different dialysis membrane on the interleukin - 8 expression" @default.
- W2370331831 hasPublicationYear "2002" @default.
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