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- W2370361451 abstract "Ubiquitination is an important way of protein degradation in vivo. Ubiquitin ligase is a key enzyme in ubiquitination process. Neuregulin receptor degradation protein 1( Nrdp1) is a new ubiquitin ligase,with ubiquitin ligase activity. Nrdp1 plays its biological functions by ubiquitination degradation or activation of the substrate molecules. It plays a key role in inhibiting cell proliferation,promoting cell apoptosis and resisting inflammatory response. Nrdp1 can regulate cell proliferation by degrading Erb B3,mediate apoptosis by degrading apoptosis inhibitory protein,and resist inflammation by degrading interferon regulatory factor and activating myeloid differentiation factor. Meanwhile,it's discovered that Nrdp1 is closely related to the pathogenesis of the diseases of cancer,nervous system diseases,hematopoietic system diseases and cardiovascular system diseases." @default.
- W2370361451 created "2016-06-24" @default.
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- W2370361451 date "2014-01-01" @default.
- W2370361451 modified "2023-09-23" @default.
- W2370361451 title "Research Progress in Studies of Neuregulin Receptor Degradation Protein-1" @default.
- W2370361451 hasPublicationYear "2014" @default.
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