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- W2370372166 abstract "Objective Aiming at atypical squamous cells(ASC) that confirmed by liquid based cytology of cervix,a further detection of high-risk HPV was conducted to investigate its value in guiding the selection of clinical management for ASC of undetermined significance(ASCUS).Methods By using hybrid capture Ⅱ(HC2) technique,362 patients with ASCUS were detected for their high-risk HPV DNA,and a colposcopic biopsy was done on suspected region to confirm the diagnosis pathologically.Results Of all 362 ASCUS patients,59(16.30%) were with cervical intraepithelial neoplasia(CIN).In 219 with positive high-risk HPV DNA,the detection rate of CIN was higher than those with negative high-risk HPV,being 23.74% versus 5.59%(χ2=22.531,P0.01).A combined detection of ASCUS with high-risk HPV could exempt 37.57% of them from unwanted colposcopic biopsy.The highest infection rate(72.92%) of high-risk HPV was noted in women of 30 years of age,which fell off along with growing old.In those with high-risk HPV,the highest detection rate of CINⅡ,CINⅢ,or ICC was in 30-40-year group,accounting for 17.44%.Conclusion High-risk HPV DNA test would be helpful for women with ASCUS detected cytologically,especially for young ones." @default.
- W2370372166 created "2016-06-24" @default.
- W2370372166 creator A5086839429 @default.
- W2370372166 date "2013-01-01" @default.
- W2370372166 modified "2023-09-22" @default.
- W2370372166 title "VALUE OF HPV DETECTION ON CLINICAL MANAGEMENT OF PATIENTS WITH ATYPICAL SQUAMOUS CELLS" @default.
- W2370372166 hasPublicationYear "2013" @default.
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