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- W2370394762 abstract "Objective:To investigate the predictive value of cord blood IgE,IL-4 and IL-6 levels in the development of atopic diseases in infants.Methods:A total of 100 pregnant women have been enrolled.Among them,70 atopic pregnant women were assigned to study group,while 30 pregnant women with no atopic family history and allergic symptoms were assigned to control group.The levels of IgE,IL-4 and IL-6 in cord blood were detected by ELISA in both groups.All the infants were followed up by telephone or in outpatient clinics at 1,3,6,12,18,24 months after birth.Details on allergic diseases were recorded.Results:The median(25%quartile-75%quartile) of cord blood IgE,IL-4 and IL-6 in the study group were 1.63(1.04-2.24)U/L,11.8(4.10-22.4) μg/mL,5.56(0.07-10.24)μg/mL,respectively;while in the control group they were 0.60(0.07-1.27)U/L,5.08(2.07-20.3) μg/mL,3.02(0.02-5.24)μg/mL,respectively.There were significant differences between the two groups(P0.05).During the follow-up period,58 infants(83%) in the study group and 7 infants(23.3%) in the control group suffered from allergic diseases,and the difference was statistically significant(P0.05).Conclusions;Increased levels of cord blood IgE,IL-4 and IL-6 may be risk factors of infant allergic diseases,and thus detecting their levels in cord blood may help to prevent the development of allergic disease." @default.
- W2370394762 created "2016-06-24" @default.
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- W2370394762 date "2013-01-01" @default.
- W2370394762 modified "2023-09-26" @default.
- W2370394762 title "Predictive Values of Cord Blood Levels of IgE,IL-4 and IL-6 in Atopic Diseases in Infants" @default.
- W2370394762 hasPublicationYear "2013" @default.
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