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- W2370438002 abstract "OBJECTIVE:To study the pharmacological action of Wuju Jiangya pills.METHODS:The blood pressure(BP) and heart rate(HR) of normal BP rat and spontaneous hypertensive rat(SHR) were taken as experimental parameters to observe the pharmacodynamic actions of Wuju Jiangya pills.Placebo control group received 0.5% sanlose,positive control group,Nuhuang Jiangya pills 2g/kg,and experimental group received Wuju Jiangya pill in dosages of 1.2,0.6,0.2g/kg,ig,qd for 15 days.The changes of BP and HR were observed 10,20,30,45,60,90,120,240min after administration of drugs.RESULTS:The effects of Wuju Jiangya pills in middle and high dosages on SHR initiated 20min and 30min after administration,then BP began to decrease and HR slowed down.The changed BP and HR would keep 3h,1h and 4h,2h respectively.CONCLUSION:Wuju Jiangya pills had no significant effects on BP and HR of normal BP mice(P0.05) but showed a little bit of tendency of hypotensive action.The pills could significantly reduced the BP and HR in SHR(P0.05) and the effect was more marked in condition of high dose." @default.
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- W2370438002 date "2002-01-01" @default.
- W2370438002 modified "2023-09-23" @default.
- W2370438002 title "Pharmacodynamic Study on Wuju Jiangya Pills" @default.
- W2370438002 hasPublicationYear "2002" @default.
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