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- W2370443247 abstract "Objective To investigate the relationship between primary hypertension and mononucleotide polymorphism of A-20C and A-6G at the promoter region of angiotensinogen gene.Methods The study covered 200 hypertension patients and 192 normotensive controls.A-20C and A-6G polymorphism of the AGT gene was determined using polymerase chain reaction-Restriction fragment length polymorphism(PCR-PFLP).Biochemical indices such as serum glucose(GLU) and total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL) and low density lipoprotein(LDL)were also measured.Results There was no significant difference between the two groups in terms of A-20C genotype(χ2=2.226,P=0.136;χ2=1.78,P=0.182)There was no significant difference between the two groups in terms of.A-6G genotype(χ2=0.012,P=0.911;χ2=0.052,P=0.82).Conclusion There was no correlation between A-20C and A-6G polymorphisms of AGT gene and primary hypertention." @default.
- W2370443247 created "2016-06-24" @default.
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- W2370443247 date "2011-01-01" @default.
- W2370443247 modified "2023-09-23" @default.
- W2370443247 title "Relationships between Mononucleotide Polymorphism of Angiotensinogen Gene at Promoter A-20C and A-6G and Primary Hypertension" @default.
- W2370443247 hasPublicationYear "2011" @default.
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