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- W2370444927 abstract "Objective To assess the significance of synovial fluid (SF) anti-cyclic citrullinated peptide antibody(CCP) in the diagnosis of rheumatoid arthritis (RA). Methods Anti-CCP was detected by ELISA in 37 serum and synovial fluid samples of RA patients and 13 synovial fluid samples of controls. Rheumatoid factor (RF) was also assayed. Some clinical parameters were recorded. The correlation of anti-CCP and those parameters was analyzed. Results The sensitivity and the specificity of SF anti-CCP were 72.9% and 92.3% respectively. There was significant difference in SF anti-CCP between RA patients and controls. SF anti-CCP had high correlation with serum anti-CCP (P0.001) and with RF in SF (P0.01). SF anti-CCP had correlation with duration of disease, but had no correlation with swollen joint count, tender joint count, DAS 28, serum RF, ESR, CRP, or Steinbrocker radiographic stage. Conclusions SF anti-CCP has satisfactory sensitivity and specificity in diagnosis of RA, independent from some clinical parameters, and has correlation with serum anti-CCP and RF in SF." @default.
- W2370444927 created "2016-06-24" @default.
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- W2370444927 date "2006-01-01" @default.
- W2370444927 modified "2023-09-22" @default.
- W2370444927 title "Significance of synovial fluid anti-cyclic citrullinated peptide antibody in the diagnosis of rheumatoid arthritis" @default.
- W2370444927 hasPublicationYear "2006" @default.
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