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- W2370475978 abstract "Objective To explore a method of establishing implanted hepatic cancer model in Wistar rats.Materials and Methods Concentrated cancerous suspension of CBRH 7919 cell lines were injected subcutaneouly into the nude mice scapular region.Then the tumor tissues were implanted into the liver of adult Wistar rats.Dexamethasone was injected intramuscular everyday at one week preoperative and two weeks postoperative,with dose of 2.5mg/d.After four weeks of this implantation,color ultrasonograph and nuclear magnetic resonance(MRI) were performed for seeking the model rats which have tumors in liver.The tumor growth and its characters were analyzed.The rats were killed for pathological examination.Results Two rats died during the operation.There are thirty-five tumors in livers of thirty-five rats (83.3%,35/42) had successfully implanted.The average diameter of tumors was (7±3)mm.All the tumors were proved hepatocellular carcinoma by pathological examination.Conclusion It is a new way to establish implanted liver tumor models and can be used widely." @default.
- W2370475978 created "2016-06-24" @default.
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- W2370475978 date "2011-01-01" @default.
- W2370475978 modified "2023-09-23" @default.
- W2370475978 title "Establishment of Implanted Hepatic Cancer Model in Wistar Rats" @default.
- W2370475978 hasPublicationYear "2011" @default.
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