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- W2370509034 abstract "Objective: To investigate the synergetic effect and possibility of spinal cord injury repaired by transplantation of olfactory mucosa and methylprednisolone in adult rat.Methods: Wistar rats with T10 spinal cord hemisection were divided into 4 groups: olfactory mucosa group(OM),olfactory mucosa in combination with mthylprednisolone group(OM+MP),methylprednisolone group(MP) and control group(CG) respectively.The functional recovery of spinal cord injury was observed with combined behavioral score(CBS) and pathological anatomy at different phases.The tissue sections were made at 5 weeks and 10 weeks postoperatively to observe the axon regeneration and the survival of olfactory ensheathing cells.Results: The CBS showed that rats treated with OM and OM+MP had more improvement than that of MP and control group at series of phases after operation 3 weeks(p0.01),but had not significant difference between OM group and OM+MP group(p0.05).The pathological section showed same results as CBS.Conclusion: The method of treating spinal cord injury by transplanted transplants of olfactory mucosa and administration of a high dose of Methylprednisolone had good curative effect,but had not significant synergetic effect." @default.
- W2370509034 created "2016-06-24" @default.
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- W2370509034 date "2006-01-01" @default.
- W2370509034 modified "2023-09-23" @default.
- W2370509034 title "Study on Repair of adult rat spinal cord injury by transplants of olfactory mucosa and administration of a high dose of Methylprednisolone" @default.
- W2370509034 hasPublicationYear "2006" @default.
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