Matches in SemOpenAlex for { <https://semopenalex.org/work/W2370509780> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2370509780 abstract "Objective To investigate the deferring aging effect and the associated mechanisms of ginkgo biloba extract(GBE) on indexes of oxidation system and the exprssion of Klotho(KL) in the brain of aging mice induced by D-gal.Methods 48 male Kunming mice were divided randomly into the normal control group,D-gal model group,GBE group and D-gal plus GBE group.All animals were administered by corresponding medicine for four weeks,respectively.The activity of SOD and the level of MDA of the hippocampus were detected by colorimetry.Immunohistochemistry and Western blotting techniques were performed to determine the exprssion of KL protein in the brain choroid.Results Compared with the control group,the expression of KL protein decreased significantly(P0.01),the activity of SOD declined obviously and the content of MDA increased clearly in aging model group(P 0.01).GBE could reverse these changes(P0.01).Conclusions This study indicates that D-gal can down-regulate the expression of KL protein in aging mice.GBE can postpone the aging by improving the activity of antioxidation and up-regulating expression of KL protein in aging mice model induced by D-gal." @default.
- W2370509780 created "2016-06-24" @default.
- W2370509780 creator A5013478611 @default.
- W2370509780 date "2010-01-01" @default.
- W2370509780 modified "2023-09-23" @default.
- W2370509780 title "Effect and mechanisms of ginkgo biloba extract on the expression of Klotho protein in the brain of aging mice" @default.
- W2370509780 hasPublicationYear "2010" @default.
- W2370509780 type Work @default.
- W2370509780 sameAs 2370509780 @default.
- W2370509780 citedByCount "0" @default.
- W2370509780 crossrefType "journal-article" @default.
- W2370509780 hasAuthorship W2370509780A5013478611 @default.
- W2370509780 hasConcept C104317684 @default.
- W2370509780 hasConcept C126322002 @default.
- W2370509780 hasConcept C134018914 @default.
- W2370509780 hasConcept C185592680 @default.
- W2370509780 hasConcept C204232928 @default.
- W2370509780 hasConcept C2776415932 @default.
- W2370509780 hasConcept C2778998842 @default.
- W2370509780 hasConcept C2779134260 @default.
- W2370509780 hasConcept C2779706397 @default.
- W2370509780 hasConcept C2780091579 @default.
- W2370509780 hasConcept C2781161787 @default.
- W2370509780 hasConcept C2993665655 @default.
- W2370509780 hasConcept C55493867 @default.
- W2370509780 hasConcept C556039675 @default.
- W2370509780 hasConcept C6856738 @default.
- W2370509780 hasConcept C71924100 @default.
- W2370509780 hasConcept C85265743 @default.
- W2370509780 hasConcept C98274493 @default.
- W2370509780 hasConcept C9832595 @default.
- W2370509780 hasConceptScore W2370509780C104317684 @default.
- W2370509780 hasConceptScore W2370509780C126322002 @default.
- W2370509780 hasConceptScore W2370509780C134018914 @default.
- W2370509780 hasConceptScore W2370509780C185592680 @default.
- W2370509780 hasConceptScore W2370509780C204232928 @default.
- W2370509780 hasConceptScore W2370509780C2776415932 @default.
- W2370509780 hasConceptScore W2370509780C2778998842 @default.
- W2370509780 hasConceptScore W2370509780C2779134260 @default.
- W2370509780 hasConceptScore W2370509780C2779706397 @default.
- W2370509780 hasConceptScore W2370509780C2780091579 @default.
- W2370509780 hasConceptScore W2370509780C2781161787 @default.
- W2370509780 hasConceptScore W2370509780C2993665655 @default.
- W2370509780 hasConceptScore W2370509780C55493867 @default.
- W2370509780 hasConceptScore W2370509780C556039675 @default.
- W2370509780 hasConceptScore W2370509780C6856738 @default.
- W2370509780 hasConceptScore W2370509780C71924100 @default.
- W2370509780 hasConceptScore W2370509780C85265743 @default.
- W2370509780 hasConceptScore W2370509780C98274493 @default.
- W2370509780 hasConceptScore W2370509780C9832595 @default.
- W2370509780 hasLocation W23705097801 @default.
- W2370509780 hasOpenAccess W2370509780 @default.
- W2370509780 hasPrimaryLocation W23705097801 @default.
- W2370509780 hasRelatedWork W1948460491 @default.
- W2370509780 hasRelatedWork W1970842390 @default.
- W2370509780 hasRelatedWork W2008004330 @default.
- W2370509780 hasRelatedWork W2145758368 @default.
- W2370509780 hasRelatedWork W2350981500 @default.
- W2370509780 hasRelatedWork W2358819618 @default.
- W2370509780 hasRelatedWork W2367349400 @default.
- W2370509780 hasRelatedWork W2369247102 @default.
- W2370509780 hasRelatedWork W2374415537 @default.
- W2370509780 hasRelatedWork W2379958908 @default.
- W2370509780 hasRelatedWork W2391037025 @default.
- W2370509780 hasRelatedWork W2415148697 @default.
- W2370509780 hasRelatedWork W2762867285 @default.
- W2370509780 hasRelatedWork W2768196429 @default.
- W2370509780 hasRelatedWork W2783124449 @default.
- W2370509780 hasRelatedWork W2784304925 @default.
- W2370509780 hasRelatedWork W2990460888 @default.
- W2370509780 hasRelatedWork W3029653004 @default.
- W2370509780 hasRelatedWork W3149669551 @default.
- W2370509780 hasRelatedWork W3162772084 @default.
- W2370509780 isParatext "false" @default.
- W2370509780 isRetracted "false" @default.
- W2370509780 magId "2370509780" @default.
- W2370509780 workType "article" @default.