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- W2370528095 abstract "AIM To study glutathion peroxidate (GSH Px) and catalase (CAT) activity of blood and liver in rat injected by Soman and discuss effect of antioxidation of Vit. A, E against free radical injury induced by Soman. METHODS Fifty male rats were randomly divided into 5 groups, negative group, positive group, Vit. A group, Vit. E group and compound group. Rats in negative and positive group were per fused with 5 mL·kg -1 oil from mouth per day; Rats in Vit. A group received 2 mL·kg -1 Vit. A as above; Rats in Vit. E group received 25 mL·kg -1 Vit. E as first; Dose of compound group was 1 mL·kg -1 Vit. A and 12.5 mL·kg -1 Vit. E. After 10 d, rats in other groups were given 0.9 LD 50 Soman from hypodemic injection except negative group. After 2 h, we did sampling from death rats. GSH Px and CAT activity of blood and liver were determined. RESULTS GSH Px activity of liver in toxicant rat injected by Soman decreased after 2 h. GSH Px and CAT activity of blood and liver increased in Vit. A, Vit. E, Vit. A and Vit. E group. CONCLUSION There is a significantly antioxidative effect of Vit. A and Vit. E against free radical injury induced by Soman in rat. It is suggested that Vit. A and Vit. E are of protective effect against free radical injury induced by Soman in rat." @default.
- W2370528095 created "2016-06-24" @default.
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- W2370528095 date "2002-01-01" @default.
- W2370528095 modified "2023-09-23" @default.
- W2370528095 title "Effect of Vit. A, E on peroxidate induced by Soman in rat" @default.
- W2370528095 hasPublicationYear "2002" @default.
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