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- W2370533900 abstract "Objective To investigate the relationship between the expression of carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1) and CD105,and the relationship of them with tumor angiogenesis in epithelial ovarian cancer.Methods The expressions of CEACAM1 and CD105 were detected by immunohistochemical method,and the microvessel density(MVD) was calculated.The correlation analysis of the expressions of CEACAM1 and CD105 was carried out in 62 specimens of epithelial ovarian cancer and 60 specimens of benign tumor tissue.Results The expressions of CEACAM1 and CD105 were higher in epithelial ovarian cancer than those in benign tumor tissue.The expressions of CEACAM1 and CD105 were positively related with pathology staging of ovarian cancer(r=0.847,0.776;P0.01),with the increase of the degree of malignancy of epithelial ovarian cancer,CEACAM1 and CD105 expression gradually increased.The expression of CEACAM1 was positively related with CD105-MVD(r=0.890,P0.01).Conclusion Overexpression of CEACAM1 may be related to the occurrence and development of ovarian cancer.CD105-MVD may be an important marker for evaluating the malignancy of epithelial ovarian cancer.CEACAM1 may stimulate tumor angiogenesis as a vascular growth factor." @default.
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- W2370533900 date "2012-01-01" @default.
- W2370533900 modified "2023-09-24" @default.
- W2370533900 title "Expression of carcinoembryonic antigen-related cell adhesion molecule 1 and CD105 in epithelial ovarian cancer" @default.
- W2370533900 hasPublicationYear "2012" @default.
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