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- W2370565568 abstract "Objective To explore the effect of adiponectin on high glucose-induced rat primary pancreaticβ-cell apoptosis and the possible mechanism.Method Rat primary islet cells were isolated and divided into several groups,andβ-cell apoptosis and mRNA expressions of some apoptosis-related genes were studied.Result Theβ-cell apoptotic rate and expressions of caspase-3 and Bax mRNA were significantly higher in HG group than in NG and HGAPN(HG plus adiponectin) group.Conclusion Adiponectin can inhibit high glucose-induced primary rat pancreaticβ-cell apoptosis and its mechanism might be related to the down regulation of Caspase-3 and Bax mRNA expression." @default.
- W2370565568 created "2016-06-24" @default.
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- W2370565568 date "2011-01-01" @default.
- W2370565568 modified "2023-09-23" @default.
- W2370565568 title "Study of adiponectin suppression of high glucose-induced SD rat primary pancreatic β cell apoptosis" @default.
- W2370565568 hasPublicationYear "2011" @default.
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