Matches in SemOpenAlex for { <https://semopenalex.org/work/W2370598532> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2370598532 abstract "To develop polysaccharide-protein conjugate vaccine for protecting Salmonella typhimurium infection,Salmonella typhimurium LH strain was fermented,then LPS was extracted with hot-phenyl method and detoxificated with 1% acetic acid at 100℃ for 90min.The O-SP mixture passed through the Superdex 200 column,first elution peak was collected as effective polysaccharide antigen.O-SP was activated with CDAP,bound to TT with ADH as a spacer,EDAC as condensation reagent.Solutions of 2.5ug of saccharide,alone or as conjugate,were injected subcutaneous three times into young mice,with a interval each 14days.Anti-LPS IgG antibodies were measured with indirected ELISA,LPS used as coating antigen.After third injection mouse anti-LPS IgG antibody titer more than 1:80 reached to 84.2%,the GMT of anti-LPS IgG antibody was 796.The results show that the immunogenicity of this conjugate vaccine was well and the TI(T cell independent) antigen related to O-SP was effectively converted into TD(T cell dependent) antigen.In addition,conjugate vaccine was also safe in mouse and gunia pigs." @default.
- W2370598532 created "2016-06-24" @default.
- W2370598532 creator A5011340657 @default.
- W2370598532 date "2006-01-01" @default.
- W2370598532 modified "2023-09-26" @default.
- W2370598532 title "Investigation of conjugate vaccine of Salmonella typhimurium O-SP bound to Tetanus toxoid (TT)" @default.
- W2370598532 hasPublicationYear "2006" @default.
- W2370598532 type Work @default.
- W2370598532 sameAs 2370598532 @default.
- W2370598532 citedByCount "0" @default.
- W2370598532 crossrefType "journal-article" @default.
- W2370598532 hasAuthorship W2370598532A5011340657 @default.
- W2370598532 hasConcept C134306372 @default.
- W2370598532 hasConcept C14086860 @default.
- W2370598532 hasConcept C147483822 @default.
- W2370598532 hasConcept C159047783 @default.
- W2370598532 hasConcept C159654299 @default.
- W2370598532 hasConcept C185592680 @default.
- W2370598532 hasConcept C197336794 @default.
- W2370598532 hasConcept C203014093 @default.
- W2370598532 hasConcept C2777351567 @default.
- W2370598532 hasConcept C2779583294 @default.
- W2370598532 hasConcept C2780801004 @default.
- W2370598532 hasConcept C2780868878 @default.
- W2370598532 hasConcept C2781065037 @default.
- W2370598532 hasConcept C32611913 @default.
- W2370598532 hasConcept C33923547 @default.
- W2370598532 hasConcept C523546767 @default.
- W2370598532 hasConcept C54355233 @default.
- W2370598532 hasConcept C86803240 @default.
- W2370598532 hasConcept C89423630 @default.
- W2370598532 hasConceptScore W2370598532C134306372 @default.
- W2370598532 hasConceptScore W2370598532C14086860 @default.
- W2370598532 hasConceptScore W2370598532C147483822 @default.
- W2370598532 hasConceptScore W2370598532C159047783 @default.
- W2370598532 hasConceptScore W2370598532C159654299 @default.
- W2370598532 hasConceptScore W2370598532C185592680 @default.
- W2370598532 hasConceptScore W2370598532C197336794 @default.
- W2370598532 hasConceptScore W2370598532C203014093 @default.
- W2370598532 hasConceptScore W2370598532C2777351567 @default.
- W2370598532 hasConceptScore W2370598532C2779583294 @default.
- W2370598532 hasConceptScore W2370598532C2780801004 @default.
- W2370598532 hasConceptScore W2370598532C2780868878 @default.
- W2370598532 hasConceptScore W2370598532C2781065037 @default.
- W2370598532 hasConceptScore W2370598532C32611913 @default.
- W2370598532 hasConceptScore W2370598532C33923547 @default.
- W2370598532 hasConceptScore W2370598532C523546767 @default.
- W2370598532 hasConceptScore W2370598532C54355233 @default.
- W2370598532 hasConceptScore W2370598532C86803240 @default.
- W2370598532 hasConceptScore W2370598532C89423630 @default.
- W2370598532 hasLocation W23705985321 @default.
- W2370598532 hasOpenAccess W2370598532 @default.
- W2370598532 hasPrimaryLocation W23705985321 @default.
- W2370598532 hasRelatedWork W2012356361 @default.
- W2370598532 hasRelatedWork W2020344926 @default.
- W2370598532 hasRelatedWork W2062467833 @default.
- W2370598532 hasRelatedWork W2075525633 @default.
- W2370598532 hasRelatedWork W2080871593 @default.
- W2370598532 hasRelatedWork W2122491596 @default.
- W2370598532 hasRelatedWork W2123431017 @default.
- W2370598532 hasRelatedWork W2130543035 @default.
- W2370598532 hasRelatedWork W2171052739 @default.
- W2370598532 hasRelatedWork W22490698 @default.
- W2370598532 hasRelatedWork W2254564701 @default.
- W2370598532 hasRelatedWork W2298597512 @default.
- W2370598532 hasRelatedWork W2353177980 @default.
- W2370598532 hasRelatedWork W2379942427 @default.
- W2370598532 hasRelatedWork W2381808820 @default.
- W2370598532 hasRelatedWork W2389619020 @default.
- W2370598532 hasRelatedWork W3080151933 @default.
- W2370598532 hasRelatedWork W3148389522 @default.
- W2370598532 hasRelatedWork W35176705 @default.
- W2370598532 hasRelatedWork W3032413071 @default.
- W2370598532 isParatext "false" @default.
- W2370598532 isRetracted "false" @default.
- W2370598532 magId "2370598532" @default.
- W2370598532 workType "article" @default.