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- W2370616853 abstract "Objective To study the relationship between autoantibodies against angiotensin Ⅱ receptor type 1(AT1-AAs)and uric acid,creatinine in essential hypertensives.Methods 344 patients with essential hypertension were selected.The AT-1-AAs in sera of patients were detected by ELISA.Serum uric acid,creatinine and urea nitrogen were detected by enzyme method.These patients were divided into 4 groups according to AT-1-AAs' titer:negative group,1∶40 group,1∶80 group,1∶160 and overtopping.Then observed the levels of uric acid and creatinine in different groups.Results The level of creatinine is gradually increasing and the level of uric acid decreasing as the increasing of AT-1-AAs concentration [creatinine(83.2±56.0),(85.3±48.9),(103.2±88.0),(144.7±136.1)μmol/L;uric acid(344.2±118.6),(332.1±126.2),(332.2±127.6),(235.0±106.3)μmol/L;all P0.05].Ordinal logistic regression analysis showed that age,the level of creatinine and uric acid were correlated with AT-1-AAs(respectively OR=1.031,2.374,0.881;all P0.05).Conclusion The AT-1-AAs were positively related to the level of creatinine and negatively correlated with the level of uric acid." @default.
- W2370616853 created "2016-06-24" @default.
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- W2370616853 date "2010-01-01" @default.
- W2370616853 modified "2023-09-24" @default.
- W2370616853 title "The Relationship Between Autoantibodies Against Angiotensin II Receptor Type 1 and Uric Acid,Creatinine in Essential Hypertensives" @default.
- W2370616853 hasPublicationYear "2010" @default.
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