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- W2370656141 abstract "The determination of the dissolution of isosorbide 5 mononitrate preparations was carried out with RP HPLC external standard method. The mobile phase was CH 3OH H 2O(1∶3), and detected at 220nm. The sample size was 150 μl. The linear range was 2～80 μg/ml and the lowest detectable concentration was 0.1 μg/ml. The RSD of the determinations was less than 1%. Two marketed preparations were tested. After non linear regression, it was found that the drug release of the extended release preparation fitted with first order equation D t = D max [70%( 1-e -k(t-t 0) )+30%]." @default.
- W2370656141 created "2016-06-24" @default.
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- W2370656141 date "1997-01-01" @default.
- W2370656141 modified "2023-09-23" @default.
- W2370656141 title "STUDY OF DISSOLUTION OF ISOSORBIDE 5 MONONITRATE PREPARATIONS" @default.
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