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- W2370697066 abstract "The protective blood brain barrier normally allows diffusion of small molecules such as oxygen and carbon dioxide, and transport of essential nutrients, but excludes large proteins and other blood constituents from the interstitial space of the CNS. However, head trauma, stroke, status epilepticus and other pathological conditions can compromise the integrity of this barrier, and allow blood proteins as large as albumin to gain access to the extracellular spaces.The appearance of serine proteases such as thrombin, tissue plasminogen activator and plasmin in the CNS have come under increasing scrutiny. Evidence now supports a role serine proteases in the sequence of events that can lead to glial scarring, edema,seizure and neuronal death." @default.
- W2370697066 created "2016-06-24" @default.
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- W2370697066 date "2002-01-01" @default.
- W2370697066 modified "2023-09-25" @default.
- W2370697066 title "Effects of serine proteases in secondary brain lesion after brain trauma" @default.
- W2370697066 hasPublicationYear "2002" @default.
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