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- W2370751107 abstract "Objective To approach the significance of pulse indicator continuous cardiac output(PiCCO) monitoring in sepsis shock after early goals directed therapy(EGDT).Methods A total of 74 sepsis shock patients with mechanical ventilation were treated with fluid resuscitation according to the EGDT and received further resuscitated with PiCCO monitoring.The enrolled patients were divided into success group and failure group according to clinic outcome 72 hours after fluid resuscitation.Hemodynamic parameters of PiCCO,urinary volumes,perfusion volumes and ScvO2 were measured and compared at baseline,and 6,24 and 72 hours after fluid resuscitation.Results At baseline and 6 hours after fluid resuscitation,there was no significant difference in perfusion volume,preload,afterload,cardiac function or SOFA score between the 2 groups.However,significantly more perfusion volume(P0.05),higher preload parameters(intrathoracic blood volume index,ITBI: P0.05;extravascular lung water index,EVLWI: P0.05;global enddiastolic volume index,GEDI: P0.05) and SOFA score(P0.05),and worse microcirculation index(ScvO2: P0.05;Lac: P0.05) were found in failure group 24 hours after resuscitation.Furthermore,72 hours after fluid resuscitation,significantly more perfusion volumes(P0.01),higher preload parameters(ITBI: P0.01;EVLWI: P0.01;GEDI: P0.01;CVP: P0.01) and SOFA score(P0.01),more urine volume(P0.05),less cardiac function(cardiac output,CO: P0.05;cardiac index,CI: P0.01;global ejection fraction,GEF: P0.05),microcirculation index(ScvO2: P0.01;Lac: P0.01) and afterload level(SVRI: P0.01) were found in failure group.Conclusion After EGDT in patients with sepsis shock,PiCCO provides sufficient hemodynamic information as well as preload,afterload,cardiac function and fluid adventure,contributing to successfully individual therapy." @default.
- W2370751107 created "2016-06-24" @default.
- W2370751107 creator A5052852385 @default.
- W2370751107 date "2013-01-01" @default.
- W2370751107 modified "2023-09-25" @default.
- W2370751107 title "The significance of pulse indicator continuous cardiac output monitoring in sepsis shock after EGDT" @default.
- W2370751107 hasPublicationYear "2013" @default.
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