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- W2370762353 abstract "Objective To find the best cut-point of FPG to predict type 2 diabetes(T2DM) and impaired glucose tolerance(IGT) and to evaluate the rationality of lowering the cut-point value. Methods The ROC analysis of FPG in 2589 subjects aged≥20 years without a previous history of diabetes from Dongcheng district in Beijing was done by OGTT. The plasma glucose and lipid profile were analyzed. Results The areas under the ROC curve for predictability of FPG were 0.949 for diabetes and 0.692 for IGT. The cut-point of FPG with the best equilibrium between sensitivity and specificity was 5.6mmol/L for diabetes and 5.2 for IGT. Compared with subjects with FPG5.6mmol/L, subjects with FPG 5.6～6.1mmol/L showed more insulin resistance, higher insulin response during OGTT, and reduced insulin secretion. Subjects with FPG 5.6～6.1mmol/L were also characterized by higher plasma triglyceride levels and reduced HDL cholesterol concentrations. Conclusions It is suitable to use 5.6mmol/L as the low limit of IFG in Chinese people in Beijing city." @default.
- W2370762353 created "2016-06-24" @default.
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- W2370762353 date "2009-01-01" @default.
- W2370762353 modified "2023-09-28" @default.
- W2370762353 title "The clinical significance of lowering the cut-point of impaired fasting glucose: In view of plasma glucose homeostasis" @default.
- W2370762353 hasPublicationYear "2009" @default.
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