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- W2370771570 abstract "Objective:To study CD40 gene polymorphism of patients with essential hypertension(EH) related with serum level of CD40 and pulse wave velocity(PWV).Methods:A total of 432 EH patients were enrolled in the study.Enzyme linked immunosorbent assay method was used to measure serum level of soluble CD40(sCD40).Taqman polymerase chain reaction(PCR) method was used to measure CD40 gene polymorphism(A/G,C/T,T/C).The relations of gene polymorphism of EH patients with serum level of CD40 and PWV were analyzed.Results:Compared with other corresponding genotypes,there were significant increase in sCD40 level in EH patients with CD40 GA genotype in A/G,CT genotype in C/T and TT genotype in T/C,P0.05~0.01.Compared with other corresponding genotypes,there were significant increase in PWV in EH patients with CD40 GG genotype in A/G,CC genotype in C/T and CC genotype in T/C,P0.05 all.Conclusion:Gene polymorphisms of CD40 are related with serum concentration of CD40 and pulse wave velocity." @default.
- W2370771570 created "2016-06-24" @default.
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- W2370771570 date "2012-01-01" @default.
- W2370771570 modified "2023-09-28" @default.
- W2370771570 title "Gene polymorphism of CD40 related with serum level of CD40 and pulse wave velocity in patients with essential hypertension" @default.
- W2370771570 hasPublicationYear "2012" @default.
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