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- W2370772885 abstract "Objective: The purpose of this study is to explore the therapy method of child refractory nephritic syndrome (CRNS) in different clinical pathology types. Methods: On the bases of correcting various kinds of factors influencing the steroid effect, such measures as steroid pulse therapy, prolonged time of using steroid, conversions of steroid types, or tadditional administration of immunosupressive agents are adopted to the patients who accord with diagosising standard of child refractory nephritic syndrome (CRNS). Results: Of the 36 case, 23 patiants have been complicated with others diseases, having side effects on the treatment, which accounts for 63.89% (23/36). Minimal changes (MCNS ) in the treatment with steroid is the most effective, up to 85.7%. The steroid resistent (SR) were found in 70% of the infants. With immunosuppressive agents added, the efficacy of the treatment could rise to 85%. A little number in treatment showed steroid depentent (SD), but the majority showed steroid resistent. Focal segmental glomerulosclerosis (FSGS) and Membranous proliferative glomerulonephritis (MPGN) failed to respond to any steroid, showing steroid resistent. Conclusion: Infections, hypoalbuminemia, and others diseases are common factors that have greatly affected steroid therapy on child refractory nephritic syndrome. The clinical remission rate of child refractory nephritic syndrome can be greatly improved after these factors are corrected. Renal pathological diagnosis is significant in guiding therapy and judging the prognosis." @default.
- W2370772885 created "2016-06-24" @default.
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- W2370772885 date "2004-01-01" @default.
- W2370772885 modified "2023-09-25" @default.
- W2370772885 title "Therapy experience with 36 cases of child refractory nephritic syndrome" @default.
- W2370772885 hasPublicationYear "2004" @default.
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