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- W2370789401 abstract "Objectives:To investigate morphologic and histopathological changes of rabbits' masseteric muscle atrophy resulted from triamcinolone for injection. Methods:30 New Zealand rabbits were randomly 1:1 assigned to one of 6 groups. Croup 1 was used as normal control, and the rest of 5 groups were injected with triamcinolone 1 mg·kg-1 at one side of masseter and with normal saline at anther side of masseter. The rabbits were sacrificed under anesthesia to collect both masseters after they were injected for 2, 4, 8, 12 and 24 weeks, respectively. The thickness of the masseter was measured by B ultrasonic technique and the masseters were weighed and then dyed with HE staining, ATP enzyme staining and NADH-TR staining, respectively. The imaging analyses were conducted by the morphologic, histopathological and histochemical examinations using optical microscopy. Results:Compared with the masseters in the normal control and at normal saline side, the triamcinolone-treated side of the masseter showed lower weights and less thickness. The reduction of the massetric wet weights and the most atrophy of the masseters aggravated maximally in the 8th week post the injection and remained the maximal worsening until the end of the 24 weeks. The HE staining found that the cellular diameters of the transected masseteric muscles were significantly reduced, and the ATP enzyme staining and NADH-TR staining showed that typeⅡfibers were shrunk, especially the IIb fibers. No significantly shrink was found in typeⅠfibers. Conclusion:Triamcinolone makes the muscle atrophy of typeⅡmuscular fibers and no significant impact on typeⅡmuscular fibers." @default.
- W2370789401 created "2016-06-24" @default.
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- W2370789401 date "2006-01-01" @default.
- W2370789401 modified "2023-09-28" @default.
- W2370789401 title "Rabbit masseteric muscle atrophy resulting from triamcinolone for injection" @default.
- W2370789401 hasPublicationYear "2006" @default.
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