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- W2370816447 abstract "The history of mouse genetics started when mice strains were imported from pet farm to Castle’s laboratory in Harvard University about one hundred years ago. Mouse genome is highly homologous to human and can be modified by various approaches. Moreover, thousands of inbred strains , mutant strains and “tool” strains have been developed. Therefore, mouse has become the key model animal for the research of development biology, functional genomics and disease mechanism. Now the mouse genome project was completed. Millions of microsatellite markers and SNPs among different inbred mouse strains were identified. The assays for the physiology and biochemistry phenotypes are constantly improving, along with the collec- tion of more and more data. These works enable the several programs for large scale genome mutagenesis, gene targeting, as well as constructing and analyzing new recombined inbred strains. These programs may become the most important studies in the biology and medicine research in the coming decades." @default.
- W2370816447 created "2016-06-24" @default.
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- W2370816447 date "2006-01-01" @default.
- W2370816447 modified "2023-09-23" @default.
- W2370816447 title "Genetic research of mouse" @default.
- W2370816447 hasPublicationYear "2006" @default.
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