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- W2370828897 abstract "Objective One hundred and fifty-six cases with adverse drug reaction(ADR) by Levofloxacin in Navy General Hospital of PLA were analyzed retrospectively from 2010 to 2013,in order to investigate the occurrence time and regularity of adverse reaction about Levofloxacin,resulting in the accumulation of the evidence for rational use of drugs in different time. Methods The medical record of 4 141 cases for hospitalized patients were analyzed retrospectively,the hour,severity,and clinical manifestations were collected,,and the data were analyzed by circular distribution. Results The incidence rate of ADR for Levofloxacin in the period of the day from 7 pm to 9 pm was up to 2.86%,the difference was statistically significant to other times(Watson-William,F=17.523,P=0.000). The severity analysis found,severe accounted for 27.27% and 25% in the period of the day from 7 pm to 9 pm and the one from 11 pm to 1 am,serious degree was higher than those at the other time(Ridit,Z=9.321,P=0.000). The ADR in clinical manifestations was different in different time,and the difference was statistically significant. Conclusion The ADR of Levofloxacin has temporal specificity,which is of guiding significance for clinical medication." @default.
- W2370828897 created "2016-06-24" @default.
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- W2370828897 date "2014-01-01" @default.
- W2370828897 modified "2023-10-03" @default.
- W2370828897 title "Analysis on temporal distribution of 156 cases of adverse drug reaction induced by levofloxacin from 2010 to 2013" @default.
- W2370828897 hasPublicationYear "2014" @default.
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