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- W2370858976 abstract "Objective To investigate the clinical effect of different dense of levobupivacaine used during continuous epidural analgesia.Methods 96 ASAⅠ～Ⅱ patients undergoing gynecology operation under epidural analgesia were randomly divided into four groups,24 cases in each group.After operation,in our departmental study,3 different concentrations of levobupivacaine(Group Ⅰ:0.125% Group Ⅱ:0.15% and Group Ⅲ:0.2%)and 0.125% bupivacacine (Group Ⅳ)combined with fentany1(4 μg/ml)were administered in continuous epidural post-operative infusion to investigate quality of analgesia,motor block and side-effects.The incidence of nausea and vomiting,VAS,MAP,SpO_2,HR and RR were respectively measured at the time of 0,4,8,12,24 and 48th hour after PCA.Blood samles were obtained and myocardial zymograms(AST,LDH,BDH,CK)were measured before operation and at 24th hour after operation.Results No statistically significant difference was noted in age,height,weight,duration of the operation between the groups.Postoperative analgesia was satisfactiory in all four groups.VAS showed no statistical difference among groups Ⅰ,Ⅱ,Ⅳ,and was significantly lower in group Ⅲ than in groups Ⅰ,Ⅱ,Ⅳ(P0.05).There were no significant differences in the changes of MAP,HR,RR and SpO_2 among the four groups.Postoperative CK was significantly different from that in preoperation(P0.01).Conclusion Background epidural infusion of 0.125%～0.2% levobupivacaine with 4 μg/ml fentanyl is satisfactory for postoperative analgesia.Levobupivacaine is less cardiotoxic than bupivacaine." @default.
- W2370858976 created "2016-06-24" @default.
- W2370858976 creator A5030169080 @default.
- W2370858976 date "2006-01-01" @default.
- W2370858976 modified "2023-09-22" @default.
- W2370858976 title "Clinical study of continuous epidural analgesia with fentanyl-levobupivacaine mixture for the treatment of postoperative pain in gynecology operation" @default.
- W2370858976 hasPublicationYear "2006" @default.
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