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- W2370860357 abstract "Objective:To study the dispersivity of acetaminophen solid dispersion by Raman spectrometry and Infrared spectrometry in order to obtain a new and simple method in examining the dispersivity of solid dispersion.Methods:Acetaminophen solid dispersion was prepared by solvent-melt method.The Raman spectra and infrared spectra of crude acetaminophen,PEG 6000,physical mixtures,solid dispersion were acquired by Raman and Fourier transform infrared spectrometers.And the spectra were compared with each other in order to find out the differences between acetaminophen solid dispersion and other materials.Results:Acetaminophen combined with PEG 6000 by hydrogen bond,and acetaminophen was dispersed in solid dispersion.Conclusion:Raman spectrometry which is fast,direct and non-destructive is an ideal method in examining the dispersivity of solid dispersion." @default.
- W2370860357 created "2016-06-24" @default.
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- W2370860357 date "2011-01-01" @default.
- W2370860357 modified "2023-09-23" @default.
- W2370860357 title "Vibrational spectrometry study on the dispersivity of acetaminophen solid dispersion" @default.
- W2370860357 hasPublicationYear "2011" @default.
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