Matches in SemOpenAlex for { <https://semopenalex.org/work/W2370867071> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2370867071 abstract "Objective To observe the effects of 3,6-dihydroxyflavone on the proliferation and apoptosis in breast cancer cell lines MCF-7 (ER+) and MDA-MB-231 (ER-),colorectal carcinoma cell lines LoVo and DLD-1,prostatic cancer cell line PC3. Methods Cell proliferation was detected by MTT assay. The morphological changes in cancer cells were observed after DAPI staining. Cell apoptosis was determined by flow cytometry after Annexin V/PI staining. Results MTT assay showed that 3,6-dihydroxyflavone could significantly inhibit the proliferation of MCF-7,MDA-MB-23,LoVo,DLD-1 and PC3 cell lines. The IC 50 value for 48 h was 16.1,15.7,29.8,12.8 and 17.8 μmol/L,respectively. Morphological observation and apoptosis detection indicated dramatic proapoptotic morphological changes and enhanced cell apoptosis rate in all 5 cancer cells after treatment with 3,6-dihydroxyflavone at the dose of 10 μmol/L for 24 h. Conclusion 3,6-dihydroxyflavone has potent anti-cancer activity and can significantly inhibit the proliferation and induce apoptosis in cancer cells." @default.
- W2370867071 created "2016-06-24" @default.
- W2370867071 creator A5006983538 @default.
- W2370867071 date "2009-01-01" @default.
- W2370867071 modified "2023-09-23" @default.
- W2370867071 title "Antiproliferative and proapoptotic effects of 3,6-dihydroxyflavone on different cancer cells" @default.
- W2370867071 hasPublicationYear "2009" @default.
- W2370867071 type Work @default.
- W2370867071 sameAs 2370867071 @default.
- W2370867071 citedByCount "0" @default.
- W2370867071 crossrefType "journal-article" @default.
- W2370867071 hasAuthorship W2370867071A5006983538 @default.
- W2370867071 hasConcept C121608353 @default.
- W2370867071 hasConcept C153911025 @default.
- W2370867071 hasConcept C185592680 @default.
- W2370867071 hasConcept C190283241 @default.
- W2370867071 hasConcept C2777527632 @default.
- W2370867071 hasConcept C2780783641 @default.
- W2370867071 hasConcept C502942594 @default.
- W2370867071 hasConcept C54355233 @default.
- W2370867071 hasConcept C553184892 @default.
- W2370867071 hasConcept C55493867 @default.
- W2370867071 hasConcept C62112901 @default.
- W2370867071 hasConcept C81885089 @default.
- W2370867071 hasConcept C86803240 @default.
- W2370867071 hasConcept C88634738 @default.
- W2370867071 hasConcept C96232424 @default.
- W2370867071 hasConceptScore W2370867071C121608353 @default.
- W2370867071 hasConceptScore W2370867071C153911025 @default.
- W2370867071 hasConceptScore W2370867071C185592680 @default.
- W2370867071 hasConceptScore W2370867071C190283241 @default.
- W2370867071 hasConceptScore W2370867071C2777527632 @default.
- W2370867071 hasConceptScore W2370867071C2780783641 @default.
- W2370867071 hasConceptScore W2370867071C502942594 @default.
- W2370867071 hasConceptScore W2370867071C54355233 @default.
- W2370867071 hasConceptScore W2370867071C553184892 @default.
- W2370867071 hasConceptScore W2370867071C55493867 @default.
- W2370867071 hasConceptScore W2370867071C62112901 @default.
- W2370867071 hasConceptScore W2370867071C81885089 @default.
- W2370867071 hasConceptScore W2370867071C86803240 @default.
- W2370867071 hasConceptScore W2370867071C88634738 @default.
- W2370867071 hasConceptScore W2370867071C96232424 @default.
- W2370867071 hasLocation W23708670711 @default.
- W2370867071 hasOpenAccess W2370867071 @default.
- W2370867071 hasPrimaryLocation W23708670711 @default.
- W2370867071 hasRelatedWork W2101146378 @default.
- W2370867071 hasRelatedWork W2348769965 @default.
- W2370867071 hasRelatedWork W2350466793 @default.
- W2370867071 hasRelatedWork W2352633755 @default.
- W2370867071 hasRelatedWork W2354858722 @default.
- W2370867071 hasRelatedWork W2355723781 @default.
- W2370867071 hasRelatedWork W2357473444 @default.
- W2370867071 hasRelatedWork W2359459995 @default.
- W2370867071 hasRelatedWork W2361171626 @default.
- W2370867071 hasRelatedWork W2363008779 @default.
- W2370867071 hasRelatedWork W2365382811 @default.
- W2370867071 hasRelatedWork W2367461549 @default.
- W2370867071 hasRelatedWork W2368520509 @default.
- W2370867071 hasRelatedWork W2371151678 @default.
- W2370867071 hasRelatedWork W2380458756 @default.
- W2370867071 hasRelatedWork W2381563779 @default.
- W2370867071 hasRelatedWork W2387195251 @default.
- W2370867071 hasRelatedWork W2392334836 @default.
- W2370867071 hasRelatedWork W3012513420 @default.
- W2370867071 hasRelatedWork W3203763843 @default.
- W2370867071 isParatext "false" @default.
- W2370867071 isRetracted "false" @default.
- W2370867071 magId "2370867071" @default.
- W2370867071 workType "article" @default.