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- W2370871758 abstract "Aim To discuss the diagnostic and prognostic values of adenosine deaminase(ADA),5'-Nucleotidase(5'-NT),transferrin(TRF),total biliary acid(TBA),leucine aminopeptidase(LAP)and prealbumin(PA)in patients with liver diseases.Methods The levels of ADA,5'-NT,TRF,TBA,LAP and PA were determined by Hitachi 7600 auto analyzer and analyzed statistically in 41 patients with acute hepatitis,78 patients with chronic hepatitis,62 patients with cirrhosis,50 patients with liver cancer and 53 healthy controls.Results The levels of ADA,5'-NT and LAP in patients with acute hepatitis or liver cancer were markedly higher than those in healthy controls(P0.01)and the levels of TRF and PA were markedly lower(P0.01)and the level of TBA was higher(P0.05).The levels of ADA,5'-NT,TBA and LAP in patients with chronic hepatitis were materially higher(P0.05)and the levels of TRF and PA were markedly lower(P0.01).The levels of ADA and TBA in patients with cirrhosis were notably higher(P0.01)and the levels of TRF and PA were markedly lower(P0.01)and the level of 5'-NT was higher(P0.05),however,the level of LAP was similar to that of the normal subjects(P0.05).The area under receiver operating characteristic curve(AUCROC)was the highest in 5'-NT in acute hepatitis.AUCROC was higher in ADA and PA in chronic hepatitis.AUCROC was higher in ADA,TBA and PA in cirrhosis.AUCROC was higher in ADA,5'-NT and PA in liver cancer.AUCROC was lower in LAP in chronic hepatitis,cirrhosis and liver cancer.Conclusion In above indexes,ADA and PA have higher values in liver disease diagnosis and can be used as routine item in library.Other five indexes besides LAP have higher clinical appliance values in hepatocirrhosis.Furthermore,the above six index can be associated with routine index.It is important for physicians to diagnose,treat,and evaluate liver status." @default.
- W2370871758 created "2016-06-24" @default.
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- W2370871758 date "2011-01-01" @default.
- W2370871758 modified "2023-09-25" @default.
- W2370871758 title "Evaluation on diagnostic and prognostic values of ADA,5'-NT, TRF,TBA,LAP and PA in patients with liver diseases" @default.
- W2370871758 hasPublicationYear "2011" @default.
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