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- W2370920072 abstract "Objective To observe the expression and localization of adenovirally delivered ciliary neurotrophic factor(CNTF)in the retina of normal rats.Methods Forty healthy rats were randomly divided into four groups:PBS group,Ad-LacZ group,Ad-CNTF group and normal control group.Adenovirus with CNTF gene were injected into rat eyeballs of experimental groups.At 1 day,14 days,28 days after intravitreal injection,eyeballs of rat were taken out.Frozen sections of tissue were made.Immunohistochemistry was conducted on the tissue sections.Results Following intravitreal injections of Ad-CNTF,CNTF immunostaining increased in retina significantly,and distributed in diffuse forms,expression of CNTF in the retina were still higher at 28 days post-injection than other control group.Conclusion Following intravitreal injection of Ad-CNTF,expression of CNTF in the retina of normal rats increases significantly,which is still higher at 28 days post-injection." @default.
- W2370920072 created "2016-06-24" @default.
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- W2370920072 date "2006-01-01" @default.
- W2370920072 modified "2023-09-22" @default.
- W2370920072 title "Expression and localization of adenovirally delivered CNTF in the retina of rats" @default.
- W2370920072 hasPublicationYear "2006" @default.
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