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- W2370945448 abstract "Objective To investigate the changes of molecular markers of coagulation and fibrinolytic system in patients with gynecological malignant tumors and their clinical significancy.Methods In comparison with 26 mormal non-pregnant women,the levels of von Willebrand Factor(vWF),platelet α-granule membrane protein(GMP-140),thrombin-antithrombin complex(TAT),plasmin-antiplasmin complex(PAP),fibrin degradation product(FDP),D-Dimer(DD),plasminogen activity(PLG),plasmin activity(PLM),activity of tissue-type plasminogen activator(t-PA),antithrombin Ⅲ(AT-Ⅲ),plasminogen activator inhibitor(PAI)and α2-antiplasmin(α2-AP) were measured in 25 patients with gynecological malignent tumors before and after operatiom.Results There were significant differences in the preoperative levels of all markers between patients with maligenant gynecological tumors and the controls.Pre-thrombotic state of coagulation and fibrinolytic system in preoperation was worsened at the first and 24th hour in postoperative patients with malignant gynecolgical tumors.Conclusions Persistent high levels of molecular markers on coagulation and fibrinolytic system would be easy to lead to thrombosis in patients with infiltrative metastasis.Monitoring above parameters is very important for investigating prethrombotic state and implementing necessary intervention to prevent thrombosis diseases." @default.
- W2370945448 created "2016-06-24" @default.
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- W2370945448 date "2007-01-01" @default.
- W2370945448 modified "2023-09-26" @default.
- W2370945448 title "Postoperative deep vein thrombosis of lower limb and changes of coagulation and fibrinolytic system before and after operation in patients with gynecological malignant tumors" @default.
- W2370945448 hasPublicationYear "2007" @default.
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