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- W2370956929 abstract "Objective To study the clinical value of anti-cardiolipin antibodies(ACA) and anti-ganglioside antibodies (AGA) in people with neuropsychiatric lupus erythematosus (NPLE). Methods 93 serum ( 33 with NPLE, 35 no neuropsychiatric manifestations of SLE and 25 no-SLE cerebrovascular disease ) and 17 cerebrospinal fluids (6 with NPLE, 5 no neuropsychiatric manifestations of SLE and 6 no-SLE cerebrovascular disease ) were examined for anti-cardiolipin antibodies by ELISA method. Results The positive rates of ACA were 90.9%(IgG) and 87.9%(IgM) in NPLE, 34.3%(IgG and IgM) in no neuropsychiatric manifestations of SLE, 52%(IgG) and 48%(IgM) in no-SLE cerebrovascular disease. There was significant difference between NPLE and others in serum (P0.05). The positive rates of ACA were 3/6(IgG) and 2/6(IgM) in NPLE ,1/5(IgG) and 1/5(IgM) in no neuropsychiatric manifestations of SLE, 2/6(IgG) and 2/6(IgM) in no-SLE cerebrovascular disease. There was not significant difference among three groups in CSF (P0.05). Sera anti-cardiolipin antibodies levels were significantly elevated in NPLE , with acute confusion state or psychiatric disorder had relatively higher levels of anti-cardiolipin antibodies than other NPLE (P0.05). Conclusions Serum anti-cardiolipin antibodies may be helpful to clinical diagnosis of NPLE." @default.
- W2370956929 created "2016-06-24" @default.
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- W2370956929 date "2008-01-01" @default.
- W2370956929 modified "2023-09-23" @default.
- W2370956929 title "Clinical value of anti-cardiolipin antibodies in neuropsychiatric lupus erythematosus" @default.
- W2370956929 hasPublicationYear "2008" @default.
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