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- W2371006912 abstract "PURPOSE: The aim of this study is to retrospectively review 6 cases of maxillofacial and cervical infections with descending mediastinitis, and to investigate the clinical manifestations, radiographic features, bacteriologic tests, treatment and prognosis of this complex infection. METHODS: 6 patients were identified from December 1998 to June 2005, and the etiology, associated systemic diseases, clinical manifestation, bacteriology, complications and treatment outcomes were analyzed. RESULTS: Of them, 4 were male and 2 were female. The average age was 47 years (ranging from 30 to 82 years). 2 patients also had diabetes. 4 of the 6 patients resulted from odontogenic infections (pericoronitis of the third molar of the mandible), 1 resulted from upper airway infection, and 1 had unknown causes. Diffuse swelling in bilateral submandibular and cervical region and abscess formation were the main clinical findings, which was followed by swelling and hyperemia in the front of the chest. Chest radiography showed a widening of the upper mediastinal shadow in 4 of 6 patients. 4 patients underwent CT scanning that displayed abscess in the mediastinum. Pus and blood culture results showed that bacillus was the main pathogen isolated. Under extensive surgical drainage, thoracic drainage and large doses of antibiotics, 4 patients were successfully treated while two died (33.3%). CONCLUSIONS: High mortality is found in this complex infection. Early diagnosis should be made through clinical and radiographic examinations. Extensive surgical drainage remains the mainstay for the treatment of deep cervical infection with mediastinitis. Bacteriologic culture is very helpful for selection of antibiotics. Supportive therapy and multidisciplinary approach is the key to salvage the patients and to decrease mortality. Supported by Shanghai Leading Academic Discipline Project (Grant No.Y0203)." @default.
- W2371006912 created "2016-06-24" @default.
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- W2371006912 date "2006-01-01" @default.
- W2371006912 modified "2023-09-23" @default.
- W2371006912 title "Diagnosis and treatment of maxillofacial and cervical infections with descending mediastinitis: Report of 6 consecutive cases" @default.
- W2371006912 hasPublicationYear "2006" @default.
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