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- W2371008098 abstract "Objective:To explore the relationship between abnormal lipid metabolism and occurrence,development of preeclampsia.Methods:The levels of total cholesterol (TC),triglyceride (TG),high density lipoprotein (HDL),low density lipoprotein (LDL),apo-A,apo-B and Lp(a) in plasma and level of free fatty acid in serum in 115 cases with preeclampsia and 50 normal pregnant women were detected and compared;24 hours urinary protein excretion was detected in cases with preeclampsia.Results:The levels of TC,TG,LDL,Apo-B,Lp(a) and FFA in mild preeclampsia group and severe preeclampsia group increased gradually with the aggravation of disease;there was significant difference in levels of TC,TG and Apo-B between severe preeclampsia group and control group (P0.05).There was significant difference in levels of LDL,Lp(a) and FFA between mild preeclampsia group,severe preeclampsia group and control group (P0.05).The levels of HDL and ApoA1 in mild preeclampsia group and severe preeclampsia group decreased gradually with the aggravation of disease;there was significant difference in levels of HDL and ApoA1 between severe preeclampsia group and control group (P0.05).Conclusion:Obvious abnormality of lipid metabolism exists in patients with preeclampsia,combined with enhancement of oxidative stress and increase of toxic products,which may harm the vascular endothelial cells;abnormal lipid metabolism is related to occurrence and development of preeclampsia closely." @default.
- W2371008098 created "2016-06-24" @default.
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- W2371008098 date "2010-01-01" @default.
- W2371008098 modified "2023-09-26" @default.
- W2371008098 title "Clinical study on changes of lipid metabolism in patients with preeclampsia" @default.
- W2371008098 hasPublicationYear "2010" @default.
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