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- W2371011331 abstract "Objective: To study the relationship between the expression of CD28/CTLA-4 in peripheral and the mechanisms of preeclampsia.Methods: 35 PE patients with preeclampsia selected as preeclampsia group and 30 normal pregnant women as controls were investigated,followed by a comparison of the expyession of CD28/CTLA-4 in peripheral by flow cytometry.Results: There was no statistical difference in the expression of CD28 between the two groups(P0.05).There was a statistical difference of the levels of CTLA-4 between the two groups(P0.05),and patients with preeclampsia in CD28/CTLA-4 ratio lower than normal control group,the difference was statistically significant(P0.05).Conclusion: The abnormal expression of CD28/CTLA-4 in patients with preeclampsia can lead to abnormal category in T cell subsets,the dysfunction of maternal-fetal immune regulation,the immune tolerance imbalance,and the occurrence of preeclampsia." @default.
- W2371011331 created "2016-06-24" @default.
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- W2371011331 date "2011-01-01" @default.
- W2371011331 modified "2023-09-26" @default.
- W2371011331 title "Expression and significance of CD28/CTLA-4 in peripheral in preeclampsia" @default.
- W2371011331 hasPublicationYear "2011" @default.
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