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- W2371036008 abstract "OBJECTIVE To study the relative bioavailability of Emtricitabine Dispersible Tablets in healthy volunteers.METHODS An oral dose of 200mg Emtricitabine Dispersible Tablets and 200mg Emtriva were given to twenty healthy volunteers in a Two-period crossover design.The drug concentrations were determined by the HPLC method.RESULTS The main pharmacokinetic parameters were as follows:Tmax were 0.77±0.24h,0.94±0.25h;Cmax were 2345.82±680.61ng·mL-1,2290.47±722.08ng·mL-1;t1/2 were 4.41±1.66h,4.25±1.75h,AUC(0~24h) were 10330.91±3105.55ng·h·mL-1,9751.35±2622.75ng·h·mL-1,respectively.The statistic results showed no significant difference between the above two preparations.CONCLUSION The two preparations were bioequivalent." @default.
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- W2371036008 date "2009-01-01" @default.
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- W2371036008 title "Human relative bioavailability of Emtricitabine Dispersible tablets" @default.
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