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- W2371039872 abstract "Objective:To explore the mechanism and clinical significant of the fluid of JianbuTongluo fumigation for controlling and treating knee osteoarthritis,and to provide the basis for the syndrome differentiation.Methods:Thirty-two Wistar rats were randomly divided into normal group,JianbuTongluo group,model group,and Voltaren group.The model of osteoarthritis knee was establishment and the rats were killed 8 weeks after treatment.The levels of TNF-α and MMP-3 in serum and synovial were detect by ELSA method and the morphological changes of cartilage was observed by pathological examination.Results:The levels of TNF-α and MMP-3 in rats' serum and synovial of model group were obviously higher than the normal group and treatment group.Conclusion:The fluid of JianbuTongluo fumigation can improve the cartilage matrix metabolism and promote repaired of cartilage by reducing the leakage of cell activity factor and thereby reducing articular cartilage damage by variety cytokines." @default.
- W2371039872 created "2016-06-24" @default.
- W2371039872 creator A5017297829 @default.
- W2371039872 date "2011-01-01" @default.
- W2371039872 modified "2023-09-28" @default.
- W2371039872 title "The Fluid of JianbuTongluo Fumigation on TNF-α and MMP-3 of Serum and Synovial Fluid in Rats with Knee Osteoarthritis" @default.
- W2371039872 hasPublicationYear "2011" @default.
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