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- W2371040631 abstract "Objective:To assess the relative efficacy and side effects of 7 kinds of triptans in the treatment of migraine.Methods: Medline,PubMed,Cochrane collaboration database,CALIS and SAGE foreign periodical net,CNKI,VIP database were searched for randomized control trials of triptans from January 1995 to June 2010.Meta-analysis was performed for the included studies using RevMan 5.0 software.Results: A total of 127 articles were searched out and 56 of them were enrolled in present meta-analysis.The pain relief rate at 2 hours and sustained efficacy at 24 hours in rizatriptan 10 mg and at 2 hours in 5 mg were significantly higher than that in placebo.All 3 doses of eletriptan(20 mg,40 mg,80 mg) had higher efficacy than placebo.Sumatriptan 50 mg,100 mg orally disintegrating tablet and 50 mg tablet were more effective than placebo,100 mg tablet was more effective than placebo except sustained pain relief rate at 24 hours.Almotriptan 12.5 mg was more effective than placebo,pain relief rate of 6.25 mg and 25 mg after 2 hours were significantly higher than that in placebo.Zolmitriptan 2.5 mg and 5 mg were more effective than placebo.In both frovatriptan 2.5 mg and naratriptan 2.5 mg,the efficacy at 2 hours were significantly higher than that in placebo.In almotriptan,eletriptan,naratriptan,zolmitriptan 2.5 mg and 10 mg tablet,spray sumatriptan 5 mg and 10 mg,the incidence rate of side effects were similar to placebo.Conclusion: All 7 kinds of triptans had certain efficacy and tolerance." @default.
- W2371040631 created "2016-06-24" @default.
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- W2371040631 date "2012-01-01" @default.
- W2371040631 modified "2023-09-25" @default.
- W2371040631 title "META-ANALYSIS OF PAIN RELIEF EFFICACY AND SIDE EFFECTS OF TRIPTANS IN THE TREATMENT OF MIGRAINE" @default.
- W2371040631 hasPublicationYear "2012" @default.
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