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- W2371044291 abstract "Objective Dynamic observed morphologic change of neuron and microcirculation in cerebral ischemia margin zone of rat.Methods The new model of regional cerebral infarction was established using the thread to embolize and fasten the internal carotid artery.Using TTC dye and single slice cerebral tissue orientation confirmed ischemia margin and center zone.Results The pathological morphologic characteristic in marginal zones of 3 h ischemia followed by 3 h reperfusion were neuron swelling,necleus excursion and dark dyed,swelling around neuron,astrocities swelling,framework of nerves tissue sparsness capillary vessel cavity dilatation,tissues swelling around blood vessel.6 h after ischemia,a strip for distinguishing central and marginal areas was not obvious and more serious cerebral tissue damage and swelling were obsered.12 h after ischemia,dividing line distinctness between ischemic center and marginal zone was clear,it showed the gap appearance and the haemorrhagic slices were also found in the central area.Conclusion The ischemic changes of neuron and microcirculation were found 3 h after ischemia,and ischemia small areas centrlized by small vessles were observed.The normal tissues and ischemic tissues were interlocked.3 h after reperfusion,swelling of ischemic marginal areas were obviously observed.12 h after ischmia,normal tissues and ischemic tissdues were clearly distinguished.And haemorrhagic infrction were found in the zone of central areas close to the marginal areas." @default.
- W2371044291 created "2016-06-24" @default.
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- W2371044291 date "2002-01-01" @default.
- W2371044291 modified "2023-09-25" @default.
- W2371044291 title "Dynamic observed morphologic change of neuron and microcirculation in focal cerebral ischemia and reperfustion of rat" @default.
- W2371044291 hasPublicationYear "2002" @default.
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