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- W2371059661 abstract "[Objective] To examine the effects of exposure to air pollutants on the peripheral blood cells, myocardial enzymes, and inflammatory response of patients with acute coronary syndrome(ACS), and to identify ACS risk factors. [Methods] Subjects included patients with ACS in Shanghai, China, who were admitted to a grade-three hospital through Cardiac Intervention Green Channel in 2008-2009. They were tested for the following biochemical indicators: general biochemical indicators, such as cholesterol, triglycerides, and low-density lipoprotein cholesterol; peripheral blood cells and inflammatory indicators, such as white blood cell count, lymphocyte percentage, and high-sensitivity C-reactive protein; myocardial injury markers: creatine kinase, troponin, and hydroxyproline glycoprotein. Atmospheric pollutants [coarse particulate(PM10), sulfur dioxide, and nitrogen dioxide] data and meteorological data were also collected. The associations between air pollutants and related risk factors of ACS were analyzed by Spearman correlation analysis. [Results] The lymphocyte percentage was closely associated with the recorded PM10 in the Spearman correlation analysis(r=0.235, P 0.05). The results of multiple stepwise regression analysis showed when using lymphocyte percentages in ACS patients as a dependent variable, PM10(P=0.011) and gender(P=0.020) were incorporated in the model. [Conclusion] Exposure to high concentrations of PM10 can lead to changes in patients' lymphocyte percentages and affect their immune system function. These findings indicate that PM10 is likely to be a risk factor for ACS." @default.
- W2371059661 created "2016-06-24" @default.
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- W2371059661 date "2014-01-01" @default.
- W2371059661 modified "2023-09-23" @default.
- W2371059661 title "Relationship of Air Pollutants with Peripheral Blood Cells, Myocardial Enzymes, and Inflammatory Response of Patients with Acute Coronary Syndrome" @default.
- W2371059661 hasPublicationYear "2014" @default.
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