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- W2371064585 abstract "OBJECTIVE To discuss the limitations of VITEK-2 Compact in the detection of the drug susceptibility of Acinetobacter baumannii to amikacin and explore the relationship between the drug resistant phenotypes and the detection result with gold standards E-test so as to offer the hospital more accurate statistics.METHODS The drug susceptibility testing results of 296 strains of A.baumannii were tested with VITEK-2 Compact AST-GN13.All the tested strains were divided into three groups according to the drug resistant phenotypes,the strains in the group A were only sensitive to amikacin,the strains in the group B were sensitive to amikacin and imipenem,and the strains in the groupc were sensitive to all the tested antibiotics except amikacin and imipenem.Each group was randomly extracted 40 strains,by the use of E-test as the gold standards,the drug susceptibility of the A.baumannii strains to amikacin was determined with K-B method.RESULTS The E-test method and the Kirby-Bauer method were consistent in the detection of A.baumannii.In the group A,the results of VITEK-2 compact differed from the results of the K-B method and E-test;in the group B,there were 39 strains being not consistent and 1 strain being consistent;in group C,there were 2 strains being not consistent and 38 strains being consistent.VITEK-2 Compact AES indicated that the results of the three methods were consistent to the 29 wild strains as the drug resistant phenotypes.CONCLUSION The study concludes that it is consistent to the results of the E-test and K-B method,thus the VITEK-2 Compact users can adopt the K-B method to detect the susceptibility of A.baumannii to amikacin." @default.
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- W2371064585 date "2013-01-01" @default.
- W2371064585 modified "2023-09-28" @default.
- W2371064585 title "Veracity of VITEK-2 Compact in detection of drug susceptibility of Acinetobacter baumannii to amikacin" @default.
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