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- W2371077098 abstract "The alternant submerged/unsubmerged cell culture of Saussurea medusa in a novel 1.8 L periodically submerged air-lift bioreactor was investigated. The bioreactor contains two layers of meshes. They provide support for cells in unsubmerged culture, but when being pulled slant the culture can be released by circulating medium from the meshes for submerged culture. The effects of the submerged/unsubmerged period on cell growth, biosynthesis of flavonoids and cell aggregate were studied. It was found that 5 min/4 h was the optimum submerged/unsubmerged period when the culture was carried out at air flow rate of 40 L/h and an inoculum (DW) of 2-3 g/L. After 20 d culture, the maximum biomass and production of flavonoids reached 9.6 g/L and 338 mg/L respectively, and the distribution of cell aggregates was the optimal as well." @default.
- W2371077098 created "2016-06-24" @default.
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- W2371077098 date "2003-01-01" @default.
- W2371077098 modified "2023-09-24" @default.
- W2371077098 title "Effect of Submerged/Unsubmerged Period on Cell Culture of Saussurea medusa in a Novel Air-lift Bioreactor" @default.
- W2371077098 hasPublicationYear "2003" @default.
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