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- W2371082016 abstract "Objective To investigate the feasibility of self-made miniature implantable spinal cord stimulation system in animal experiment. Methods Twenty healthy adult SD rats were selected.The spinal cord stimulation electrode was placed on the dorsal epidural C2 cervical spinal cord,and the battery and stimulation device were implanted under the skin.Neurological behavior scoring(BBB score) and inclined plane test were conducted before operation(0 h) and 12 h,24 h and 36 h after operation,and the body weight was measured.The stimulation parameters(voltage,pulse width and frequency) were determined 12 h,24 h and 36 h after operation. Results There was no significant difference in the stimulation parameters among the time points of 0 h,12 h and 24 h(P0.05),while there were significant differences between the time points of 0 h and 36 h(P0.05).There were significant differences in the results of BBB score,inclined plane test and body weight measurement between the time points of 0 h and 12 h(P0.05),while there was no significant difference between the time points of 0 h and 24 h and 36 h(P0.05).There was no significant adverse effect in rats during the experiment. Conclusion The self-made miniature implantable spinal cord stimulation system is safe,and is suitable for animal experiments." @default.
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- W2371082016 date "2011-01-01" @default.
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- W2371082016 title "Experimental study of feasibility of miniature implantable spinal cord stimulation system" @default.
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