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- W2371101141 abstract "AIM:To study the protective effect of Qilong Capsule (Radix Astragali, Lumbricus, and Radix Salviac Miltiorrhizae, erc.) (QLC) on cerebral ischemia in rat. METHODS: Thrombotic ischemia (PITCI) and middle cerebral artery occlusion (MCAO) induced by photo chemical in rats was used to observe the protective effect of QLC on ischemia stroke and common carotid artery occlusion (CCAO) rats was used to analyse the effect of QLC on blood brain barrier (BBB) permeability. RESULTS: QLC 0.6g/kg, 0.3g/kg and 0.15g/kg could improve the abnormal behavior of PITCI rats and decrease the infarction area, QLC 0.6g/kg and 0.3 g/kg could improve the abnormal behavior of MCAO rats and decrease the infarction area ( P0.05,P0.01 compared with vehicle). QLC 0.6g/kg, 0.3g/kg could also decrease water content in the brain of PITCI rats ( P0.05,P0.01 compared with vehicle). QLC 0.6g/kg, 0.3g/kg could significantly reduce the permeability for evans' blue (EB) of CCAO rats ( P0.05, P0.01 , compared with vehicle). CONCLUSIONS: QLC can protect the brain ischemic injury." @default.
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- W2371101141 date "2004-01-01" @default.
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- W2371101141 title "Effect of Qilong Capsule on experimental cerebral ischemia in rats" @default.
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